The world's most concentrated exosome skin booster.
Bioactives for cells, by cells.
Developed and manufactured in Sydney, Australia.
Exosomes are nature's encrypted messengers — nano-scale vesicles that carry bioactive instructions between cells.
They deliver lipids, proteins, and RNA to support rejuvenation, restoration, and resilience. Every cell type produces them. No other signalling vehicle speaks so fluently to skin.
Our exosomes are not human-derived. Not animal-derived. Not plant-derived. They are cell-cultured — grown with intention, not extraction.
This is exvivo.
The highest available concentration of cell-culture derived exosomes, formulated to support the appearance of rejuvenation, resilience, and regeneration.
Purity defines the formulation. Every functional effect is driven by exosomes alone — no added HA, niacinamide, or vitamin C.
Visible results in seven days, after a single application. The efficacy of human-derived exosomes, the scalability of plant-derived, at a lower cost than either — with guaranteed consistent supply.
| KEY ACTIVE INGREDIENTS | AVERAGE QUANTITY PER 5mL |
|
|---|---|---|
| EXOSOMES | Cell-culture derived. The highest available concentration for topical use. | > 1 TRILLION |
| LIPIDS | Cholesterol, sphingomyelin, ceramide phospholipids. Support skin barrier integrity. | |
| PROTEINS & PEPTIDES | CD9, CD63, CD81, annexins, HSP70. Support antioxidant activity, cellular uptake, and ECM integrity. | 2,259 PROTEINS 17,749 PEPTIDES |
| miRNAs | miR-451, miR-16, miR-193a. Support collagen structure, regulate pigmentation, reduce redness. | |
| VITAMINS, ORGANIC ACIDS & MINERALS | Essential micronutrients and cofactors. Support cell metabolism, collagen structure, and antioxidant defence. | 3 VITAMINS 17 AMINO ACIDS 7 MINERALS |
Market-leading concentration per mL. Rich bioactive cargo of peptides, proteins, and miRNA. None of the regulatory, ethical, or supply barriers of other exosome sources.
We are the only company producing cell-culture-derived exosomes at scale.
| CRITERIA | HUMAN-DERIVED EXOSOMES |
PLANT-DERIVED EXOSOMES |
CELL-CULTURE DERIVED EXOSOMES |
|---|---|---|---|
| EFFICACY | ✓ | ✕ | ✓ |
| PERMITTED UNDER REGULATION | ✕ | ✓ | ✓ |
| SCALABILITY | ✕ | ✓ | ✓ |
| AFFORDABILITY | ✕ | ✓ | ✓ |
Sourced from adipose tissue or placenta. Prohibited in major markets (EU, UK, US, China). Fragile supply, donor variability, difficult to scale. Low concentration per mL.
Biologically incompatible with human skin. Lack key bioactive cargo — peptides, growth factors, miRNA. Minimal effect on renewal. Low concentration per mL.
All benefits, no barriers. We are the only company producing cell-culture-derived exosomes at scale.
Compared head-to-head with ExoMide — the gold standard exosome skin booster in aesthetic clinics — exvivo delivers 67× the exosome concentration.
This extraordinary density underpins the visible skin improvements observed in dermatological evaluations.
| EXOMIDE | EXVIVO | |
|---|---|---|
| EXOSOME ORIGIN | Human-derived (adipose tissue) | Cell-cultured fibroblasts (quail) |
| EXOSOME CONCENTRATION PER 5ML VIAL | 15 billion exosomes | Over 1 trillion exosomes (a 67× difference) |
| MECHANISM OF ACTION | Effect driven by a blend of exosomes and actives (hyaluronic acid, niacinamide, panthenol, glutathione). | Effect driven purely by exosomes. |
Independent dermatological evaluations confirm fast, measurable improvement across key markers of skin quality after a single treatment.
-34%
APPEARANCE OF REDNESS
Visible improvement in skin tone uniformity and reduction of redness.
-10% / -12% / -20%
WRINKLE DEPTH / LENGTH / WIDTH
Measurable reduction in wrinkle depth, length, and width.
Visibly increased
SKIN ELASTICITY
Visible lift and improved facial contour definition.
Participants: 8 (male and female, aged 30–40).
Application: 5mL of Exvivo Exosome Skin Booster.
-34%
-20%
UV/Porphyrin Facial Scan
Skin Texture Topography
Surface Texture Analysis
Vascular Mapping — Periorbital Region
Participants: 2 (female, 40-60).
Application: 5 mL of pure Exvivo Exosome Skin Booster.
Note: These results are from preliminary evaluations, further testing is underway.
Independent clinicians and formulators testing exvivo in their own practices — reporting results that surpass anything they've previously observed.
"I've been in this industry for 18 years, and I've never seen anything like it. I'm usually a 'meh' guy, skeptical of new technologies and products, but the results we saw after a single application of Exvivo's exosomes were faster and more impressive than anything I've come across."
"Adding Exvivo's cell-cultured exosomes to our conditioner has been a game-changer. We've seen noticeably stronger, thicker hair and faster scalp recovery - results we hadn't been able to achieve with any other ingredient."
"Exvivo's cell-cultured exosomes are the first we've seen that deliver human-level efficacy with plant-like practicality - it's the perfect balance we've been looking for."
Cell-culture production & quality control
Cargo mirrors the natural lipid and protein architecture of human skin.
Serum-free suspension culture of non-human fibroblast cells, absent of FBS and non-GMO.
Demonstrated improvements to fine lines, wrinkles, elasticity, and tone uniformity.
Market-leading concentration per mL and bioactive cargo.
Stable particle size around 145 nm (mono-modal distribution), uniform batch-to-batch.
Manufactured in accordance with HACCP, cosmetic GMP and GCCP standards.
2,259 identified proteins across key functional categories
| CATEGORY | PROTEINS |
|---|---|
| COLLAGEN PROTEINS | |
| COL12A1 | Collagen Type XII Alpha 1 |
| COL6A1 | Collagen Type VI Alpha 1 |
| COL6A2 | Collagen Type VI Alpha 2 |
| COL6A3 | Collagen Type VI Alpha 3 |
| COL5A2 | Collagen Type V Alpha 2 |
| COL18A1 | Collagen Type XVIII Alpha 1 |
| COL1A2 | Collagen Type I Alpha 2 |
| MATRIX METALLOPROTEINASES | |
| MMP2 | Matrix Metalloproteinase-2 |
| MMP1 | Matrix Metalloproteinase-1 |
| MMP14 | Membrane-type Matrix Metalloproteinase |
| TIMP1 | Tissue Inhibitor of Metalloproteinases 1 |
| GROWTH FACTORS | |
| TGFBI | Transforming Growth Factor Beta-Induced |
| LTBP1 | Latent TGF-Beta Binding Protein 1 |
| LTBP2 | Latent TGF-Beta Binding Protein 2 |
| IGFBP3 | Insulin-like Growth Factor Binding Protein 3 |
| IGFBP5 | Insulin-like Growth Factor Binding Protein 5 |
| IGFBP7 | Insulin-like Growth Factor Binding Protein 7 |
| CTGF/CCN2 | Connective Tissue Growth Factor |
| PDGFRB | Platelet-Derived Growth Factor Receptor Beta |
| ANTIOXIDANT PROTEINS | |
| SOD1 | Superoxide Dismutase 1 |
| SOD2 | Superoxide Dismutase 2 |
| PRDX1 | Peroxiredoxin 1 |
| CYTOKINES | |
| IL6ST | Interleukin-6 Signal Transducer |
| TNFRSF1A | TNF Receptor Superfamily Member 1A |
| CSF1 | Colony Stimulating Factor 1 |
| LIF | Leukemia Inhibitory Factor |
| OTHER RELEVANT PROTEINS | |
| FN1 | Fibronectin |
| ELN | Elastin |
| LOXL2 | Lysyl Oxidase-Like 2 |
| SERPINE1 | Plasminogen Activator Inhibitor-1 |
| CLU | Clusterin |
| HSP90AA1 | Heat Shock Protein 90 Alpha |
| HSPA1A | Heat Shock Protein 70 |
| ANXA1 | Annexin A1 |
| VITAMIN | CONCENTRATION (mg/L) |
|---|---|
| Vitamin B1 (Thiamine) | Detected |
| Vitamin B2 (Riboflavin) | Detected |
| Vitamin E (Tocopherol) | Detected |
| AMINO ACID | CONCENTRATION (mg/L) |
|---|---|
| Aspartic Acid | Detected |
| Serine | Detected |
| Glutamic Acid | Detected |
| Glycine | Detected |
| Arginine | Detected |
| Threonine | Detected |
| Alanine | Detected |
| Proline | Detected |
| Tyrosine | Detected |
| Valine | Detected |
| Lysine | Detected |
| Isoleucine | Detected |
| Leucine | Detected |
| Phenylalanine | Detected |
| Methionine | Detected |
| Cysteine | Detected |
| Tryptophan | Detected |
| MINERAL | CONCENTRATION (mg/L) |
|---|---|
| Calcium | Detected |
| Iron | Detected |
| Magnesium | Detected |
| Phosphorus | Detected |
| Potassium | Detected |
| Sodium | Detected |
| Zinc | Detected |
